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Even safety data on TB-500 (synthetic TB4) is relatively scarce, with only a few studies reporting the potential side effects of its systemic application: In a 2010 study in 10 participants, TB4 caused occasional mild to moderate symptoms like headache and dizziness but no serious reactions or toxicities, even at doses up to 1260mg, administered daily for up to two weeks

Although the exact reason behind ageing is yet to be clear, several evidences suggest on damage-based theories

Squires RF, Saederup E

In controlled research environments, it is used as a model compound in studies examining peptide interactions, cellular processes, and experimental biological systems

Peripheral blood amyloid- involved in the pathogenesis of Alzheimers disease via impacting on peripheral innate immune cells