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Researchers focusing on facial skin rejuvenation sometimes inject in the abdominal or upper arm areas nearest the face and neck

When taken in conjunction with a diet and exercise plan, you may achieve up to a 5- to 10-pound weight loss

However, anecdotal reports from online forums cited in a 2025 systematic review included anxiety and panic attacks, depression and anhedonia, insomnia, heart palpitations, fatigue and weakness, and loss of appetite

It works best as part of a consistent sleep hygiene routine

Some people notice improvements within a few days, while others may take several weeks depending on their levels and overall health