Shi ZZ, Habib GM, Rhead WJ, Gahl WA, He X, Sazer S, Lieberman MW
The molecule was developed by Frank Ng's group at Monash University and Metabolic Pharmaceuticals in Australia during the 1990s and 2000s as a potential anti-obesity drug intended to isolate the lipolytic region of hGH without activating the growth hormone receptor or raising IGF-1.nnIn published preclinical work, the fragment has been shown to stimulate lipolysis, suppress lipogenesis, and modulate the beta-3 adrenergic receptor pathway in adipose tissue rather than acting through the classical hGH receptor
Many protocols call for nightly injections before bed to align with the natural GH release during deep sleep
it's about letting the pharmacokinetics guide the protocol
In fact, it had been documented more than ten years earlier that when ascorbic acid and glutathione are together in the presence of the hexoxidase [ascorbate oxidase] described by Szent-Gyorgyi the glutathione wholly protects the vitamin from oxidation, whilst it is itself oxidized at a rate which, with the same concentration of enzyme, is exactly the same as the rate with which ascorbic acid is oxidized when alone. (Hopkins and Morgan 1938)