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As a monoclonal antibody, bimagrumab requires refrigerated storage (2-8 degrees C) and protection from light
81.7% of patients achieved more than 5% weight loss compared to 0% placebo
In clinical trials of Wegovy, about 2-3% of adults and 4% of adolescents reported gallstones
The primary evidence-based interventions remain: Weight loss through caloric restriction and increased physical activity (target 710% body weight reduction) Dietary modification , including reduced sugar and saturated fat intake Management of associated conditions such as diabetes and dyslipidaemia Alcohol : for NAFLD, keep within UK low-risk drinking guidelines (no more than 14 units per week, ideally less or none)
The biggest change for people continues to be the fact that they think about food less and are more calm about food choices, portions and ordering
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