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Whether the more rare adverse events differ between the different agents can only be answered by using observational cohort data from a very large group of patients and a longer follow-up time
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Sima AAF, Calvani M, Mehra M, et al
First, it allows the gastrointestinal system to adapt to the medication's effects on gastric motility and emptying, thereby minimizing common adverse effects such as nausea, vomiting, diarrhea, and abdominal discomfort
doi: 10.1007/s12011-017-1105-0 95 LiangL.ChenJ.XiaoL.WangQ.WangG
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