Water retention often decreases during this phase
Reference: Dimet-Wiley AL, Latham CM, Brightwell CR, Neelakantan H, Keeble AR, Thomas NT, Noehren H, Fry CS, Watowich SJ (2024)
Around 30 years of age, estrogen levels begin to decline, and there are corresponding changes in the skin
The selectivity is documented in the foundational paper: a peer-reviewed European Journal of Endocrinology study demonstrating that Ipamorelin stimulates growth hormone selectively without elevating ACTH, cortisol, or prolactin, which is exactly why it has become the default selective secretagogue in modern peptide medicine
However, its important to remember that B12 injections arent a magic solutionthey work best when combined with a balanced diet and regular exercise