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Drug Enforcement Agency (DEA) announced its intent to classify the active compounds (mitragynine and 7-hydroxymitragynine) in kratom as Schedule I controlled substances

This approach can be especially helpful for certain patients, like those who are highly sensitive to medications and might get nausea or other side effects easily

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Once stabilized, maintenance doses are typically administered every one to three months

The first was substances with enough of a safety track record that the agency felt comfortable letting compounders use them while the final list was assembled