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Immunogenicity associated with metreleptin treatment in patients with obesity or lipodystrophy

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Excess adipose tissue particularly visceral fat is associated with reduced testosterone levels and impaired fertility in men, making effective weight management especially relevant to male health

Importantly, the researchers found that supplementing the diet in the preclinical models with vitamin B12 and folic acid increased the levels of syntaxin 17 in the liver and restored its role in autophagy

When side effects do occur, they are often mild and related to the injection itself, such as redness, pain, or swelling at the injection site