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A 2018 Ohio Medicaid audit found that PBMs retained $223.7 million in spread pricing on generic drugs over a single year, with some generics marked up by more than 1,000% over pharmacy acquisition cost

However, the magnitude of weight loss is modest both in T2D and in obesity without diabetes

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Semaglutide is an FDA-approved medication used to support weight loss in adults who meet specific health and body mass index (BMI) criteria