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Guidelines have evolved considerably from routine medication cessation in 2023 to GLP-1 RA continuation with individualised risk assessment in 20242025, illustrating increasing acknowledgment that certain theoretical risks may be underestimated
Some women find that GLP-1 medications feel stronger or produce more side effects during hormonal transitions
*Eligible patients lost an average of 15% of their body weight (-33.6 lbs) in a 68-week clinical trial evaluating 2.4 mg semaglutide, when paired with diet and exercise
But once you discontinue one, that fullness signal can become less pronounced, which may lead to eating more, said hormone and weight loss specialist Peter Balazs, MD
Lilly has submitted orforglipron to regulators in over 40 countries, with submission for type 2 diabetes in the U.S
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