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PMID: 189 TangXLinJWangGLuJ

In a 2023 paper published in the Annals of the Rheumatic Diseases, Zhu and colleagues identified individuals with knee OA and comorbid type 2 diabetes mellitus from a cohort of more than 40,000 participants in the Shanghai Osteoarthritis Cohort study

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Microdosing compounded protocols intentionally start lower0.5 to 1.0 mg weeklyto extend the assessment phase and minimize early side effect burden