Mounjaros prescribing information states that the medication delays gastric emptying and has been associated with gastrointestinal adverse reactions, sometimes severe
However, precedent suggests that mild to moderate adverse GI events are not a major barrier to uptake of a promising metabolic therapy
But where semaglutide acts on one receptor (the glucagon-like peptide-1, or GLP-1, receptor), and tirzepatide on two (GLP-1 and the gastric inhibitory polypeptide, or GIP, receptors), retatrutide has been nicknamed Triple G for its ability to work on three hormone receptors (those for GLP-1 and GIP, as well as the glucagon, or GCG, receptor)
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If you have any doubts or questions about the medication, consult your healthcare provider for guidance