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Takahashi 2012
IRP2 expression is significantly upregulated in the midbrain substantia nigra of PD mice, increasing TFR1, FTH, and p53 levels, while decreasing SLC7A11 and GPX4 levels, leading to ferroptosis and disruption of the amino acid antioxidant system in dopaminergic neurons
Stimulates natural growth hormone release in research models, supporting studies on muscle growth, fat metabolism, recovery, and anti-aging through dual GHRH and ghrelin receptor pathways
Discovered in 1977 (Schoenenberger)
) is excellent
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