This triple-agonist approach is designed to help reduce hunger, improve satiety, support insulin sensitivity, and increase calorie expenditure
The primary end point was the percentage change in body weight after 72 weeks
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Pending successful completion, FDA approval could come as early as 2027, which would make retatrutide the first approved triple-agonist medication
[6] Stephens FB, et al, 2006b: Carbohydrate ingestion augments L-carnitine retention in humans