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Baekdal TA, Borregaard J, Hansen CW, Thomsen M, Anderson TW
Mitochondrial-derived reactive oxygen species and oxidized mtDNA are potent activators of the NLRP3 inflammasome, driving maturation of IL-1 and IL-18, which in turn enhance Th1 and Th17 responses essential for protection against Candida albicans and Aspergillus fumigatus (Patel et al., 2018)
Commonly reported effects include flushing, mild headache, water retention, temporary numbness or tingling, and injectionsite redness
Scar tissue develops where healing occurred from previous injections
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