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Although it is possible to take individual supplements of lysine and methionine, it is preferable to consume them as part of a balanced formulation of essential amino acids so that the normal balance of all amino acids in the blood is maintained.

For confirmed B12 deficiency without neurological involvement , the standard regimen comprises 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks, followed by maintenance doses every two to three months for those with irreversible causes like pernicious anaemia

Warnings Not recommended for use by pregnant and lactating women

doi: 10.7326/ANNALS-24-02174-JC, 65

Sources: Khavinson VK, et al