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10.2337/dc08-1309 98
Surface modification further improves their biocompatibility, tumor-specific targeting, and potential for drug delivery
Upon binding to IGF-1R, the peptide initiates multiple intracellular signaling cascades, including the phosphoinositide 3-kinase (PI3K)/Akt/mTOR pathway, which regulates protein synthesis and cell growth, and the mitogen-activated protein kinase (MAPK) pathway, which controls cell proliferation and survival
Thus, reductions in energy intake with GLP-1Rbased pharmacotherapies reflect not only diminished appetite but may also involve a concomitant shift in food preference toward less energy-dense foods
How does carnitine work in the body
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