Potential improvement in fertility and menstrual regularity In PCOS, excess weight and insulin resistance disrupt the delicate hormonal balance needed for regular ovulation
Additionally, managing blood sugar may lead to worsening diabetic retinopathy , another vital concern
In a study conducted by the University of Alabama at Birmingham, mice treated with semaglutide lost over 13% of their body weight but regained 14% after stopping the treatment
In addition to incretin effects, controlled glucagon receptor activation increases energy expenditure and lipid mobilization, amplifying weight loss while maintaining glycemic stability
View Source Biochemical and Biophysical Research Communications Mitochondria-related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation 2016 DOI: 10.1016/j.bbrc.2016.05.058 PMID: 27191634 Ming W, Lu G, Xin S, et al