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Moreover, transgenic mice over-expressing SDF-1 become resistant to streptozotocin-induced diabetes (61), further suggesting that SDF-1 may have some metabolic effects

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Data obtained in animal models support the idea that GLP-1 reduces sympathoexcitation and induces natriuresis, both processes associated with hypertension

Doctors warn that GLP-1s can cause muscle loss in addition to fat loss