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The cholinergic system in the pathophysiology and treatment of alzheimers disease

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Un metaanlisis de 76 ensayos y ms de 100 000 participantes mostr un riesgo 1,5 veces superior de enfermedad vesicular y biliar, especialmente con dosis altas y tratamientos prolongados. La hipoglucemia es frecuente cuando se combinan con otros hipoglucemiantes, pero no cuando se emplean solos, segn un estudio reciente del Departamento de Veteranos en U.S.A. La pancreatitis se ha notificado de forma anecdtica y rara, posiblemente relacionada con colecistitis

The cytosolic GSTs are profusely present and have been divided into divergent classes based on their genesis, catalytic amino-acid residue, sequence similarity, and substrate specificity ( Figure 1 )

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