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Drought stress regulates the sulfur assimilation pathway, which results in differential accumulation of the primary sulfur metabolism compounds (e.g., glutathione) and the secondary sulfur metabolism compounds (e.g., '-phosphoadenosine 5'-phosphate, PAP) (Estavillo et al

As such, the model was used to simulate how long it would take pharmacologically and toxicologically relevant concentrations of doxorubicin to yield a 70% reduction in GSH concentration, indicative of impaired cellular antioxidant defence, protein binding and cell death 19

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Why it happens: The needle nicks a small capillary, causing blood to leak under the skin