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The patent ultimately lapsed permanently due to non-payment of the 2019 maintenance fee
Reactive astrogliosis plays essential roles in both attracting and containing neuroinflammation, and is critical for wound closure, fibrotic scar formation, erecting glia limitans barrier delineating the damaged tissue and supporting postlesional regeneration and plasticity
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In particular, Lutetium 177 PSMA therapy has shown encouraging results in men with advanced and metastatic disease who have exhausted standard treatment lines
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