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Uncommon side effects include constipation, diarrhea, irregular heartbeat, fatigue, and anxiety

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The route of administration affects the side-effect experience

Specifically, it acts as an electron carrier in metabolic pathways such as glycolysis, the Krebs cycle, and oxidative phosphorylation

However, some people find that stronger retinol products can cause dryness or irritation, particularly when first introduced into a routine