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Description

In the SURPASS-2 study, the three doses of tirzepatide (5, 10, and 15 mg once weekly) were tested with the GLP-1RA semaglutide (1 mg once weekly) as a comparator in patients not optimally controlled on monotherapy with metformin (71)

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This version produces a long, sustained elevation of GH levelsless like a natural pulse and more like a steady, continuous "bleed." The choice between them fundamentally changes the physiological conditions you're studying

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