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In patients who develop unexplained lethargy, vomiting, or changes in mental status, hyperammonemic encephalopathy should be considered and an ammonia level should be measured [seeContraindications (4)andWarnings and Precautions (5.6, 5.9)]
6.7 Dose Adjustments in Special Populations Adjustments may be necessary for patients with renal or hepatic impairment
A., Kamal, M
Clinical trial data show that while fat mass accounts for the majority of weight loss, some lean mass reduction also occurs, which could potentially affect muscle function
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