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[13] [14] Animal and laboratory studies suggest GLP-1 agonists may have anti-inflammatory and anti-fibrotic properties, potentially mediated through effects on hepatic stellate cells and Kupffer cells

Various techniques, such as incorporating a cell-penetrating peptide (CPP) sequence or lipid conjugation, were employed to facilitate the intracellular delivery of the peptides 43

These benefits were independent of baseline HbA1c and occurred without an increased risk of hypoglycemia [94]

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On the other hand, if progress has stalled, theyll help identify potential roadblocks whether its side effects, dietary habits, or how well youre tolerating the medication