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A rare gain of function variant of hepatic lipase attenuates hypercholesterolaemia and atherosclerosis in mice via an LDL receptor-independent mechanism, Cardiovascular Research, 121 , 7, (1024-1035), (2025)

As per the researchers, Tesamorelin is a synthetic growth hormone-releasing hormone that acts on the anterior pituitary gland to stimulate the endogenous growth hormone secretion. (6) Studies suggest that the peptide may potentially cause a 69% increase in total growth hormone levels (apparently assessed via area under the curve - AUC) and a purported 55% increase in the mean pulse area of the growth hormone

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