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Tretinoin is one of the most powerful retinoids for treating acne, sun damage, or fine lines - among many other skin concerns

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Rare but serious side effects may include: Pancreatitis Gallbladder problems Kidney injury from dehydration Severe allergic reactions Contact your provider immediately if you experience severe abdominal pain or persistent vomiting

Studies have suggested that increased susceptibility to KBD in selenium-deficient populations might result from a reduced antioxidant protection associated with polymorphisms in GPX genes (60, 61), but polymorphisms in other genes have also been implicated (62)

10.1016/j.bcp.2024.116382 30 DolmatovaE