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Gene Therapy, Clinical Trials and Lessons Learned

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Although several compounds successfully prevent coagulation of blood, each type of anticoagulant works by mediating different aspects of the coagulation pathway (i.e., heparin prevents coagulation by inhibiting the formation of thrombin, whereas EDTA prevents coagulation by chelating calcium in blood [39])

3 Resistance to chemotherapy caused by detoxification by GSH has been postulated, 56 suggesting that there may be possible benefits of selectively decreasing intracellular GSH in tumors to enhance the therapeutic effect of chemotherapy

*Correspondence: Yun Sun, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers