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Here is what patients should know: Who Should NOT Use Direct Meds Semaglutide Pregnant or breastfeeding women Children and adolescents under 18 Patients with personal or family history of medullary thyroid carcinoma or MEN2 Patients with severe gastrointestinal conditions (e.g., gastroparesis) Anyone currently taking other GLP-1 receptor agonists without provider oversight Always consult your doctor before starting semaglutide

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Across these trials, tirzepatide delivered dose-dependent improvements in glycemic control and body weight, often surpassing comparators like semaglutide and dulaglutide (43)(44)

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Exenatide stretched that measure to about 2.5 hours3 sufficient for therapy but requiring twice-daily injections that placed a significant burden on patients