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In phase 3 adult clinical trials, most notably the SURMOUNT-1 study, tirzepatide produced significant and sustained reductions in body weight and metabolic parameters

At a 50% penetration rate, a 68-week course of Mounjaro would (in this ideal, nave assumption) bring the obesity rate to the lowest level its been since 1981

In the OASIS 1 trial, subjects receiving oral semaglutide (50 mg) lost 17.4% of their body weight at 68 weeks , while the placebo group achieved only 1.8% weight loss

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They may feel that drinks are less appealing, alcohol tastes different, or they simply forget to drink in situations where they normally would have