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AST significantly improved Morris water maze test performance in a dose-dependent manner, inhibited the accumulation of amyloid 1-42 and malondialdehyde levels

Bidirectional transmission in the GBA plays a major role in modulating brain dysfunction, maintaining symbiosis with the host and modulating innate as well as adaptive immune responses The normal gut microbiota synthesizes microbial metabolites and neurotransmitters that interact with host cells including intestinal epithelial cells (IECs) and immune cells

As shown in Figure 4A, BPC-157 (1 g/mL10 g/mL) was found to significantly increase the proliferation of HUVECs in a concentration-dependent manner after 48 hours of treatment

How Gut Inflammation Actually Works (and Why Peptides Fit) The intestinal barrier is a single-cell-thick layer held together by tight junction proteins: claudin-2, occludin, and zonula occludens-1 (ZO-1)

Cell Metab , 21: 756763, 2015