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Conduct regular check-ins to support safety and treatment goals
There is a downward spiral of deconditioning which can worsen symptoms of PoTS
In fact, many people regularly get injections with vitamin B12
Phase III randomized controlled trials demonstrated significantly increased pain-free sun exposure time with afamelanotide use in EPP patients (compared to placebo users)
This implies that estrogen stabilizes the central clocks rhythmicity, preventing it from responding to acute external cues
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