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World Psychiatry 17 , 316329 (2018)

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This includes management of blood glucose levels, weight, cardiovascular risk factors, comorbidities and complications

In the kidney, dual GLP-1R/GIPR stimulation attenuates MCP-1, IL-6, and tumor necrosis factor (TNF)- expression and down-regulates SGLT2 messenger ribonucleic acid (mRNA), potentially reinforcing natriuresis and glycosuria when GLP-1RA are combined with SGLT2 inhibitors [26]

This might include: Slowly stopping the drug Eating well Staying active Getting support Summary Table For Side Effects Maximising Results with GLP-1s for Craving and Weight Control Healthy eating, physical activity, and behavioural support can improve overall treatment outcomes