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Inhibition of the Xc-system, inactivation of GPX4 and overloading of iron ions are the three most critical factors leading to ferroptosis

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Food and Drug Administration (FDA) (2016)

Notably, however, the unstable product flavan-3,3,4-triol ( 4 ) is converted mainly into the by-products epidihydroquercetin ( 9 ), dihydroquercetin ( 10 ) and quercetin ( 11) 13 , while the transformation into the coloured anthocyanidin has only been observed as a minor side reaction in vitro 11,12,13 or in vivo by engineered microorganisms 6,16