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Figures were generated in Chimera 1.14
In addition to its role as a key factor for the structural integrity of ribosomes, Zn plays a number of other important bio-physicochemical roles in plants, including gene regulation and activation, protein synthesis, involvement in carbohydrate metabolisms, and morphological and anatomical participation in bio-membranes (Zaheer et al., 2020a)
To understand the underlying mechanisms, inhibitors targeting the Notch pathway (DAPT) and NF-B pathway (BMS) were also applied to HUVEC and murine CLI models
Samples were split for baseline and GCL activity measurements
-15.2% versus -2.6% and plateau around week 60
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