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This peripheral mechanism makes them theoretically safer than immunosuppressive drugs or immune-modulating biologics in autoimmune populations
Conclusion Oral peptides have gradually become the future trend of peptide drug development.While SNAC, as a permeation enhancer, leads the way in the development of oral peptides from scratch, whether it can replicate the excellent track record of semaglutide tablets to other peptide drugs needs to be carefully considered
doi: 10.1038/nrcardio.2014.59 53 SarzaniRGiuliettiFDi PentimaCSpannellaF
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Because clinical trials are limited in size and scope, rare or delayed effects may not appear until after a drug is used by thousands or millions of people
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