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Levels of GSH and GSSG in livers of mice in Figure 2A and Supplemental Figure 1, C and D were measured using Glutathione Assay Kit (Cayman Chemical, 703002)
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FIGURE 1 Hemostasis (Phase I) is a clotting process in which platelets reach the injury site to adhere to collagen type 1 and activate, releasing glycoproteins that cause their aggregation (Oguntibeju, 2019) and resulting in the release of transforming growth factor- (TGF-), platelet-derived growth factor (PDGF), endothelial growth factor (EGF), and fibroblast growth factor (FGF) (Ezhilarasu et al., 2020)
Half patients with RA under anti-TNF- can successfully discontinue treatment after achieving remission [144, 145], while this is less feasible for patients with established RA [145]