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Obesity drives more than 200 downstream diseases, yet we have historically treated those conditions one at a time and in silos, says Ania Jastreboff, MD, PhD, professor of medicine & pediatrics (endocrinology) at the Yale School of Medicine, director of the Yale Obesity Research Center, and lead investigator, in a release

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The logic is to front-load exposure while the tissue is remodeling, then taper to a maintenance rhythm that sustains the effect at a fraction of the vial cost

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