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It has been suggested that keratinocytes, through the release of biological mediators, proopiomelanocortin (POMC)-derived peptides, basic fibroblast growth factor, and endothelins, regulate proliferation and differentiation of melanocytes and stimulate melanogenesis through receptor-mediated signalling pathways [20]
& Gao, K
These may be costly and time-consuming, without the guarantee of desired results
IGF-1 LR3 is hypothesized to mitigate these risks by supporting neuronal survival and improved cardiac output
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