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There is also a mechanism for generalised input from the wider public: each month interviewers seek feedback on the questions from all respondents, who are representative of the population in Great Britain

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The Cochrane Collaboration Risk-of-Bias tool was used for quality assessment of the RCTs [18], including sequence generation, allocation concealment, blinding, incomplete outcome data, and selective outcome reporting

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Collagen has antioxidant properties that may help combat this oxidative stress, theoretically supporting the health of melanin-producing cells