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Primary prevention of cardiovascular and heart failure events With SGLT2 inhibitors, GLP-1 receptor agonists, and their combination in type 2 diabetes
These likely result from both peptides effects on angiogenesis, endothelial protection, and inflammation reduction
Stupnisek M et al
However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)
L-carnitine specifically may help produce energy for workouts, improve heart health, and even help ease PCOS symptoms
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