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Minoxidil is primarily a vasodilator

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Additionally, the nuclear export signal (NES) in KEAP1 has been shown to be important for NRF2 regulation, as it was found to facilitate the transport of the NRF2-KEAP1 complex out of the nucleus, which terminates NRF2-mediated antioxidant signaling after stress [16]

If a patient experiences side effects, their doctor may suggest they stay on the same dose for longer to give their body more time to adjust, Dr