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So I was scratching my head a little bit. The IJO paper was a retrospective cohort study of adults with obesity who had been prescribed a GLP-1 therapy, specifically Saxenda and Ozempic
9 Detailed Analysis of the Violation The "Excel" Problem: The inspection found that "Excel worksheets used to perform chromatogram calculations were not retained" and "several recent Excel spreadsheets used to perform suitability and assay calculations were deleted".9 Excel is a powerful tool, but in a CGMP environment, it is considered "software" that requires validation
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Finally, studies published prior to 2018 were included only if they provided foundational pharmacokinetic or pharmacodynamic data on GLP-1 receptor distribution in the CNS or on the initial development of acylated GLP-1 analogs
Often called the bodys master antioxidant, glutathione plays a central role in neutralizing free radicals, supporting detoxification, and maintaining cellular health
