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While antibiotics are effective, long-term use is discouraged due to concerns about antibiotic resistance and the potential disruption of healthy gut flora

Beyond energy production, NAD+ also supports several important biological processes including: Activating longevity pathways called sirtuins Supporting DNA repair mechanisms Improving mitochondrial function Helping regulate metabolic health Unfortunately, NAD+ levels naturally decline as we age

Collectively, these results suggested that injection of GSH-high hES-MSCs sorted by FreSHtracer lead to enhanced regenerative potential in a chondral defect animal model

Authors' contributions MvA, RM and IB designed the study

Skolmowska, D., Gbska, D., Koota, A., & Guzek, D