Contrave may show initial weight loss within 2-4 weeks, with peak effects usually achieved by week 12-16
A phase II trial involving capmatinib and nabulizumab as secondary treatments for advanced/metastatic EGFR wild-type NSCLC patients, who had not received anti-PD-1/PD-L1 before, revealed that a group with elevated MET expression (evidenced by immunohistochemistry in 50% of tumor cells = 3 + or gene copy number (GCN) 5 or IHC in METex14 + = 2 +) exhibited a six-month PFS rate of 68.9%
Hair thinning has been reported, likely related to rapid weight loss rather than the compound itself, as explored in the GLP-1 hair loss guide
They may be able to recommend other ways to help you manage it
Resistance training can involve lifting weights, using resistance bands, or doing bodyweight exercises that require strength (like squats, crunches, or pushups) Maintaining muscle mass helps prevent the decrease in daily calorie burn that comes from losing that lean tissue
