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Via TGR5, UDCA inhibits ERK1/2 phosphorylation, blocking the non-canonical TGF /WWP2 pathway to downregulate fibrosis-related genes (COMP, FOXP2) and reduce collagen I/VI synthesis (Reilly-O'Donnell et al., 2024)

This compound is supplied solely for laboratory and R&D purposes

Diarrhea-predominant and constipation-predominant irritable bowel syndrome: current prescription drug treatment options

In addition, YAP/TAZ is also regulated by metabolic pathways, which may help explain the important role of glutamine metabolism in ferroptosis [89]

Following these best practices helps ensure consistent dosing, reduced discomfort, and predictable results over time