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Adding a medication like tirzepatide, which also affects insulin and glucose, can make blood sugar levels even more unpredictable, increasing the risk of hypoglycemia (low blood sugar)
Combined oral contraceptives Also known as 'the pill', these medications include a combination of hormones that help prevent unwanted pregnancy in women and people assigned female at birth
A 2025 systematic review and meta-analysis in Reviews in Endocrine and Metabolic Disorders found that tirzepatide (the active ingredient in Mounjaro and Zepbound) reduced hsCRP by approximately 33% and IL-6 by approximately 18% compared to placebo across patients with and without diabetes. A growing body of research suggests this effect occurs through direct action on the NF-B pathway, a master switch of inflammation
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