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Second, the strength of tirzepatides evidence is exactly what makes an apples-to-apples ranking against an investigational amylin analog impossible: you cannot fairly rank a fully-approved drug against a candidate whose stand-alone efficacy stops at Phase 2

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As a standalone medication, current data suggest cagrilintide produces less weight loss than both Wegovy and Zepbound

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What if, for the right patient, the smarter first step is something else entirely