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It inhibits NOTCH1 signaling by using its GCT activity to cleave a -glutamyl-cysteine bond at glutamate 1669 of the immature NOTCH receptor, thereby preventing the essential S1 cleavage and subsequent activation ( FIGURE 6 The physiological importance of this mechanism is underscored by severe developmental phenotypes upon its disruption

While you might know it for its skin brightening reputation, there's so much more to this powerhouse ingredient that might just surprise you

Glutathione is a naturally occurring antioxidant in the body that helps to neutralize free radicals and protect cells from damage

Weinstain R, Slanina T, Kand D, Klan P

Involvement of catalase in the protective benefits of metformin in mice with oxidative liver injury